GRAPE SEED  might be useful for lowering LDL cholesterol, improving varicose veins, lessening atherosclerosis & lowering high blood pressure. Flavonoids found in red wine have been reported to protect the heart. They may inhibit the oxidation of LDL cholesterol. LDL oxidation can lead to hardening of the arteries or atherosclerosis. Studies have demonstrated a relationship between flavonoid intake from foods like grapes and a reduced risk of death from coronary heart disease.