ADVIL can cause analgesic-induced renal papillary necrosis can result. The kidneys shut down. Many kidney doctors caution PKD'rs against the long term use of over the counter pain relievers such as aspirin, paracetamol, tylenol, phenacetin, non-steroidal anti-inflammatory drugs (NSAIDs), or others that impair kidney function.

↓ kidney functioning
↓ liver functioning