ALDOMET methyldopa, caution with tricyclic antidepressants (TCAs, monoamine oxidase inhibitors (MAOIs) with methyldopa ↑ headaches, ↑ BP, hallucinations. Cocaine, dobutamine, dopamine, norepinephrine, ↑ BP, ephedrine, epinephrine, phenylpropanolamine, phenylephrine, methoxamine, metaraminol interactions.

↑ lithium toxicity
↑ psychosis
↓ iron absorption
↓ hypoglycemic tolbutamide